Key result
Aggressive blood pressure control resulting in low diastolic blood pressure is associated with increased cardiovascular events due to a J-curve effect across 11 reviewed articles.
Why the study?
Does aggressive blood pressure control reduce cardiovascular events in patients with hypertension?
Does aggressive blood pressure control reduce cardiovascular events in patients with hypertension?
Aggressive blood pressure lowering may be harmful due to a J-curve effect, increasing cardiovascular events at very low diastolic and systolic pressures.
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May support avoiding very low DBP targets in hypertension; leaves open confirmation in prospective trials.
Steven G. Chrysant (2011) conducted a review in Hypertension. Aggressive blood pressure control was evaluated. Aggressive blood pressure control resulting in low diastolic blood pressure is associated with increased cardiovascular events due to a J-curve effect across 11 reviewed articles.
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