Key result
This review explores the historical perspective and potential underlying signaling mechanisms of arterial baroreflex resetting during exercise in physiological and pathophysiological conditions.
Why the study?
What are the underlying signaling mechanisms of arterial baroreflex resetting during exercise in humans?
What are the underlying signaling mechanisms of arterial baroreflex resetting during exercise in humans?
This review summarizes the historical perspective and underlying signaling mechanisms of arterial baroreflex resetting during exercise in humans.
Answers are grounded in this paper and cite their sources.
Summarizes baroreflex resetting mechanisms; leaves open validation and clinical translation in disease.
The arterial baroreflex (ABR) resets during exercise in an intensity-dependent manner to operate around a higher blood pressure with maintained sensitivity. This review provides a historical perspective of ABR resetting and the involvement of other neural reflexes in mediating exercise resetting. Furthermore, we discuss potential underlying signaling mechanisms that may contribute to exercise ABR resetting in physiological and pathophysiological conditions.
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Raven et al. (2019) conducted a review in Arterial baroreflex resetting during exercise. This review explores the historical perspective and potential underlying signaling mechanisms of arterial baroreflex resetting during exercise in physiological and pathophysiological conditions.
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