Key result
Obesity increases severe COVID-19 and ICU risk by impairing lung volumes and cardiac hemodynamics.
Why the study?
Patients with obesity are at increased risk of severe COVID-19 infection and intensive care unit admission, prompting a review of cardio-respiratory pathophysiological aspects and clinical management.
This review highlights the cardio-respiratory pathophysiological mechanisms linking obesity to severe COVID-19 and proposes clinical management strategies for this high-risk population.
Supports closer monitoring of obese COVID-19 patients; leaves open whether mechanism-targeted interventions improve outcomes.
Obesity is a significant public health concern with higher morbidity. Obesity patients are at risk of severe COVID-19 infection and obesity is a higher risk factor for intensive Care Unit admission in COVID-19 infection. Obesity status affects lung volumes, cardiac structure and hemodynamics. Obesity is associated with a low inflammation state, endothelial dysfunction, hyperinsulinaemia and metabolic disorders. The authors review cardio-respiratory pathophysiological aspects involved in obesity and propose clinical management in obese patients infected by COVD-19.
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Fayssoil et al. (2020) conducted a review in COVID-19 and Obesity. Obesity increases the risk of severe COVID-19 infection and intensive care unit admission by negatively impacting cardio-respiratory pathophysiology, including lung volumes and cardiac hemodynamics.
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