Key result
Obesity displays a strong correlation with critical illness and major severity of COVID-19 manifestations.
Why the study?
Overall obesity displayed a strong correlation with critical illness and severe COVID-19 manifestations, prompting an examination of preventive and therapeutic potential in managing obesity-related complications.
Does obesity increase the risk of adverse outcomes and severe illness in patients with COVID-19?
Does obesity increase the risk of adverse outcomes and severe illness in patients with COVID-19?
Obesity is strongly correlated with critical illness and severe manifestations of COVID-19, likely due to chronic inflammation, hypercoagulation, and ventilation difficulties.
Answers are grounded in this paper and cite their sources.
Obesity signals higher COVID-19 severity risk in observational data; leaves open causality and whether targeted interventions improve outcomes.
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations. SUMMARY: Obesity and metabolic disorders are closely linked to chronic systemic inflammation. The adipose tissue constitutes a source of cytokines, which configure a low-grade inflammation and a hypercoagulation status; in addition, diagnosis and care of obese patients are often complicated by excess weight and ventilation difficulties. Key Messages: This review aims to examine the intersection between obesity and adverse outcomes of COVID-19, in order to investigate its preventive and/or therapeutic potential in the management of obesity-related COVID-19 complications.
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Gammone et al. (2021) conducted a review in COVID-19 and Obesity. Obesity was evaluated on Critical illness and major severity of COVID-19 manifestations. Obesity displays a strong correlation with critical illness and major severity of COVID-19 manifestations.
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