Key result
Moderate to severe TR in LVSD is linked to independent excess mortality.
Why the study?
The mutual relation and independent prognostic role of tricuspid regurgitation in left ventricular systolic dysfunction remain debated, and whether significant TR is merely a marker or a therapeutic target is unclear.
Population
Patients with left ventricular systolic dysfunction and tricuspid regurgitation
Design
Review
Authors
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May flag high-risk LV systolic dysfunction patients; leaves open whether TR intervention improves survival.
Tricuspid regurgitation in patients with left ventricular systolic dysfunction is a frequent and prognostically significant condition that independently worsens survival, suggesting it may be a crucial therapeutic target rather than just a marker of advanced disease.
Margonato et al. (2021) conducted a review in Tricuspid Regurgitation and Left Ventricular Systolic Dysfunction. Moderate to severe tricuspid regurgitation in the context of left ventricular systolic dysfunction is a frequent condition associated with independent excess mortality.
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