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December 1, 1990Hypertension273 citations

"White coat" versus "sustained" borderline hypertension in Tecumseh, Michigan.

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SJStevo JuliusAMAlfonso MejiaKJKrista Jones

Key Result

White coat hypertension (7.1% prevalence) and sustained hypertension (5.1%) shared similar characteristics, including faster heart rates and higher vascular resistance compared to normotensives.

Key Points

  • This research aims to compare characteristics between individuals with white coat hypertension and those with sustained hypertension.
  • Survey conducted with 737 young subjects in Tecumseh, Michigan, measuring clinic and home blood pressures over 7 days.
  • Hypertension defined using specific systolic and diastolic thresholds in clinic settings and home blood pressure readings in the top decile.
  • Assessment of historical blood pressure data from earlier ages (5, 8, 21, and 23 years) along with physiological metrics like heart rates and plasma levels.
  • 7.1% of subjects had white coat hypertension, and 5.1% had sustained hypertension.
  • Both groups exhibited significantly higher systemic vascular resistance and minimal forearm vascular resistance compared to normotensive individuals.
  • The white coat hypertensive group had lower HDL levels, while both groups showed higher triglycerides and insulin/glucose ratios.

Study Design

Type

Cross-Sectional (n=737)

Multicenter

No

Structured PICO

What is the prevalence and clinical profile of white coat versus sustained borderline hypertension in young untreated adults?

P
Population
737 young subjects not receiving treatment for hypertension (387 men, 350 women, average age 31.5 years) in Tecumseh, Michigan.
I
Intervention
Clinic and self-monitored home blood pressure measurement (14 readings in 7 days).
C
Comparator
Normotensive subjects.
O
Outcome
Prevalence of white coat and sustained hypertension, and comparison of hemodynamic and metabolic characteristics.surrogate

White coat hypertension is common in young adults and is associated with similar hemodynamic and metabolic abnormalities as sustained borderline hypertension, suggesting it is not a benign condition.

Main Result

Absolute Event Rate: 7.1% vs 5.1%

Abstract

During a survey of young subjects not receiving treatment for hypertension in Tecumseh, Michigan, clinic and self-monitored blood pressures taken at home (14 readings in 7 days) were obtained in 737 subjects (387 men, 350 women, average age 31.5 years). Hypertension in the clinic was diagnosed if the clinic blood pressure exceeded 140 mm Hg systolic or 90 mm Hg diastolic. In the absence of firm criteria for what constitutes hypertension at home, subjects whose average home blood pressure was in the upper decile of the whole population were considered to have hypertension at home. By these criteria, 7.1% of the whole population had "white coat" hypertension (i.e., high clinic but not elevated home readings). The prevalence of "sustained" hypertension (i.e., high readings in the clinic and at home) was 5.1%. Subjects with white coat and sustained borderline hypertension in Tecumseh were very similar. Both groups showed, at previous examinations (at ages 5, 8, 21, and 23 years), significantly higher blood pressure readings than the normotensive subjects. As young adults (average age 33.3 years), the parents of both hypertensive groups had significantly higher blood pressure readings than the parents of normotensive subjects. Both hypertensive groups had faster heart rates, higher systemic vascular resistance, and higher minimal forearm vascular resistance. Both hypertensive groups were more overweight, had higher plasma triglycerides, insulin, and insulin/glucose ratios than normotensive subjects. The white coat hypertensive group also had lower values of high density lipoprotein than the normotensive group. White coat hypertension is a frequent condition.(ABSTRACT TRUNCATED AT 250 WORDS)

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Cite This Study

Julius et al. (1990) conducted a cross-sectional in Borderline hypertension (n=737). White coat hypertension vs. Sustained hypertension and normotension was evaluated on Prevalence of white coat and sustained hypertension. White coat hypertension (7.1% prevalence) and sustained hypertension (5.1%) shared similar characteristics, including faster heart rates and higher vascular resistance compared to normotensives.

synapsesocial.com/papers/6a149eb14a5923a97cdf069ehttps://doi.org/10.1161/01.hyp.16.6.617
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