Key result
Increased procedural experience with TAVI (>135 procedures) was an independent predictor of 30-day survival (HR 6.7; 95% CI 1.2-18.1; P=0.03), reducing 30-day mortality from 13.3% to 5.9%.
Why the study?
Does procedural experience improve outcomes and reduce complications in high-risk patients undergoing transcatheter aortic valve implantation?
Population
270 high-risk patients with aortic stenosis undergoing transcatheter aortic valve implantation in Vancouver…
Comparison
Transcatheter aortic valve implantation by… vs First half of TAVI experience (patients 1-135)
Design
Cohort
Follow-up
30-day
Authors
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Supports TAVI learning curve in observational data; leaves open optimal volume thresholds before practice change.
Cohort (n=270)
No
Does procedural experience improve outcomes and reduce complications in high-risk patients undergoing transcatheter aortic valve implantation?
Absolute Event Rate: 5.9% vs 13.3%
p-value: p=0.04
TAVI outcomes, including procedural success and 30-day mortality, significantly improve with procedural experience, highlighting a clear learning curve effect.
Gurvitch et al. (2011) conducted a cohort in aortic stenosis (n=270). Transcatheter aortic valve implantation (TAVI) vs. First half of experience (patients 1-135) was evaluated on 30-day mortality (p=0.04). Increased procedural experience with TAVI (>135 procedures) was an independent predictor of 30-day survival (HR 6.7; 95% CI 1.2-18.1; P=0.03), reducing 30-day mortality from 13.3% to 5.9%.
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