Key result
A 28-year-old woman with eclampsia had a markedly elevated cardiac troponin I of 2,518 ng/L without acute coronary syndrome, demonstrating non-ischemic troponin elevation in pregnancy.
Case Report (n=1)
No
Markedly elevated cardiac troponin I can occur in severe preeclampsia and eclampsia without acute myocardial infarction, highlighting the need for careful interpretation alongside clinical signs and echocardiography.
Caution needed interpreting troponin in eclampsia; case report leaves open prevalence and mechanisms of non-ischemic elevation in pregnancy.
A markedly raised cardiac troponin I (cTnI) in a patient is always alarming and usually suggests significant myocardial damage, as seen in acute myocardial infarction. There are, however, other circumstances where raised cTnI may be encountered without overt myocardial necrosis. Prior studies have evaluated serum cTnI levels in preeclampsia, eclampsia and normotensive healthy pregnant women in order to define their diagnostic value. Other factors, such as altered renal function, as in preeclampsia, may also affect the serum troponin levels, leading to misdiagnosis and incorrect management. We highlight the diagnostic and management difficulties faced in the management of our patient who presented with raised cTnI following multiple eclamptic fits, without other signs of an acute cardiac event. J Med Cases. 2017;8(7):207-210 doi: https://doi.org/10.14740/jmc2836w
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Ho et al. (2017) conducted a case report in Eclampsia (n=1). Magnesium sulphate and emergency cesarean section was evaluated on Cardiac troponin I (cTnI) peak level. A 28-year-old woman with eclampsia had a markedly elevated cardiac troponin I of 2,518 ng/L without acute coronary syndrome, demonstrating non-ischemic troponin elevation in pregnancy.
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