November 1, 2000BJOG An International Journal of Obstetrics & Gynaecology

Cardiac troponin I in pre‐eclampsia and gestational hypertension

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Why the study?

Are serum cardiac troponin I levels elevated in pregnancies complicated by hypertension compared to normotensive pregnancies?

Population

69 pregnant women, including 26 with hypertension in pregnancy and 43 normotensive women.

Comparison

Hypertension in pregnancy vs Normotensive pregnancy

Design

Cross-sectional

Authors

SFS FlemingMerck & Co., Inc., Rahway, NJ, USA (United States)TOThomas W. O’GormanHealth Service Executive JFJoseph D. FinnLeeds Teaching Hospitals NHS Trust

Discussion

Member takes

Implication

Suggests subclinical myocardial injury in hypertensive pregnancies; leaves open whether troponin measurement improves risk stratification or outcomes.

Structured PICO

Are serum cardiac troponin I levels elevated in pregnancies complicated by hypertension compared to normotensive pregnancies?

Population

69 pregnant women, including 26 with hypertension in pregnancy (at least two readings of systolic blood pressure > 140 mmHg and diastolic blood pressure > 90 mmHg) and 43 normotensive women.

Intervention

Hypertension in pregnancy (with and without significant proteinuria)

Comparator

Normotensive pregnancy

Outcome

Serum cardiac troponin I levelsurrogate

Serum cardiac troponin I is elevated in hypertensive disorders of pregnancy, suggesting some degree of cardiac myofibrillary damage.

Cite This Study

Fleming et al. (2000) studied this question.

synapsesocial.com/papers/6a207bbe04d2adee4bf4951e https://doi.org/10.1111/j.1471-0528.2000.tb11658.x

Topics

Hypertension management

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Implication

Suggests subclinical myocardial injury in hypertensive pregnancies; leaves open whether troponin measurement improves risk stratification or outcomes.

Cardiac troponin I in pre‐eclampsia and gestational hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Cardiac troponin I in pre‐eclampsia and gestational hypertension

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider