Key result
The HOPE-4 study is a cluster randomized trial designed to evaluate whether a community-based, multifaceted intervention can improve the Framingham Risk Score at 12 months in 1,376 participants.
Why the study?
Does a community-based multifaceted intervention package reduce cardiovascular risk scores in people with hypertension compared to usual care?
RCT (n=1,376)
cluster
Yes
Does a community-based multifaceted intervention package reduce cardiovascular risk scores in people with hypertension compared to usual care?
This rationale and design paper outlines a cluster randomized trial evaluating a community-based intervention to reduce cardiovascular risk in patients with hypertension in low- and middle-income countries.
No takes yet. Share an insight, caveat, or question.
Addresses evidence gap for hypertension care in LMICs; extends prior RCTs to community-level interventions once completed.
Schwalm et al. (2018) conducted an RCT in hypertension (n=1,376). community-based, multifaceted intervention package vs. usual care was evaluated on change in Framingham Risk Score after 12 months. The HOPE-4 study is a cluster randomized trial designed to evaluate whether a community-based, multifaceted intervention can improve the Framingham Risk Score at 12 months in 1,376 participants.