What question did this study set out to answer?

To review the historical evolution, current treatment strategies, long-term survival, and residual cardiovascular complications in patients with repaired tetralogy of Fallot.

August 29, 2019F1000ResearchOpen Access

Current outcomes and treatment of tetralogy of Fallot

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Authors

JVJelle P. G. van der VenErasmus MC EBEva van den BoschHeidelberg University ABAd J.J.C. BogersCardiac Surgery

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Implication

Review reports high long-term survival alongside frequent residual complications in repaired tetralogy of Fallot, highlighting the challenge of optimizing pulmonary valve replacement timing.

Key Points

To review the historical evolution, current treatment strategies, long-term survival, and residual cardiovascular complications in patients with repaired tetralogy of Fallot.
Reviewed contemporary surgical and catheter-based intervention protocols implemented since the advent of surgical repair in 1954.
Synthesized long-term clinical outcome data focusing on late mortality, right ventricular diagnostic assessments, and re-intervention criteria.
Current surgical management strategies achieve a 30-year survival rate ranging from 68.5% to 90.5%.
Late post-repair complications remain frequent, predominantly involving pulmonary regurgitation, right ventricular outflow tract obstruction, and ventricular arrhythmias requiring re-interventions.
Establishing the optimal timing for pulmonary valve replacement before irreversible right ventricular dysfunction sets in remains difficult due to poorly understood chamber interactions and biological mechanisms.

Cite This Study

Ven et al. (2019) studied this question.

synapsesocial.com/papers/6a14e3ba253bd9cd3ce62786 https://doi.org/10.12688/f1000research.17174.1

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Implication

Review reports high long-term survival alongside frequent residual complications in repaired tetralogy of Fallot, highlighting the challenge of optimizing pulmonary valve replacement timing.

Current outcomes and treatment of tetralogy of Fallot

Discussion

Member takes

Implication

Key Points

Cite This Study

Current outcomes and treatment of tetralogy of Fallot

Discussion

Member takes

Implication

Key Points

Cite This Study

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