Key result
Permanent pacing with an effective rate >70 beats/min prevented torsades de pointes, whereas programmed lower rates ≤70 beats/min were not protective in a review of 18 cases.
Why the study?
What is the minimal pacing rate that prevents acquired torsades de pointes in patients with permanent pacemakers?
Population
18 patients with permanent pacemakers who developed acquired torsades de pointes, excluding events \u2leq 1…
Design
Case_series
Authors
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Rates ≤70 bpm may fail to prevent TdP despite pacing; hypothesis-generating and challenges consensus on safe drug initiation in pacemaker recipients.
What is the minimal pacing rate that prevents acquired torsades de pointes in patients with permanent pacemakers?
In patients with permanent pacemakers, a programmed lower rate of >70 beats/min may be required to protect against acquired torsades de pointes, provided pause-promoting features and oversensing are avoided.
Pinski et al. (2002) conducted a review in Acquired long QT syndrome with torsades de pointes (n=18). Permanent pacing was evaluated on Occurrence of torsades de pointes at specific pacing rates. Permanent pacing with an effective rate >70 beats/min prevented torsades de pointes, whereas programmed lower rates ≤70 beats/min were not protective in a review of 18 cases.
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