Key result
Lowering pacemaker stimulation rate is linked to ~60% less device utilization versus standard fixed pacing.
Why the study?
Does lowering the stimulation rate or using search hysteresis reduce pacemaker utilization in patients with intermittent bradycardia and a single lead pacemaker?
Population
229 patients with ventricular pacing and 19 patients with intermittent bradycardia and single lead pacemakers
Comparison
Pacing at 50 beats/min, hysteresis sensing 50… vs Fixed rate pacing at 70 beats/min
Design
Cohort
Follow-up
Four periods of 14 days for the prospective cohort
Authors
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May support lower base rates or search hysteresis to minimize pacing; hypothesis-generating pending randomized confirmation.
Does lowering the stimulation rate or using search hysteresis reduce pacemaker utilization in patients with intermittent bradycardia and a single lead pacemaker?
Effect estimate: 60% reduction
p-value: p=< 0.05
Optimizing stimulation mode and rate, such as lowering the base rate or using search hysteresis, significantly reduces pacemaker utilization and allows for more intrinsic heart activity in patients with intermittent bradycardia.
Rosenqvist et al. (1993) studied Intermittent bradycardia (n=248). Reduced stimulation rate (50 beats/min) and search hysteresis vs. Fixed rate pacing at 70 beats/min was evaluated on Pacemaker utilization (60% reduction, p=< 0.05). Reducing the pacemaker stimulation rate from 70 to 50 beats/min reduced pacemaker utilization by 60% (P<0.05), and search hysteresis decreased utilization by 33% (P<0.05).
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