Key result
Having 4 abnormal global electric heterogeneity parameters was associated with a 6.4% (95% CI, 5.5-7.3) decline in left ventricular ejection fraction and increases in LV mass and volumes.
Why the study?
Is ECG global electric heterogeneity associated with abnormalities in cardiac structure and function in a community-based cohort?
Cohort (n=14,609)
Is ECG global electric heterogeneity associated with abnormalities in cardiac structure and function in a community-based cohort?
Effect estimate: 6.4% decline (95% CI 5.5-7.3)
ECG global electric heterogeneity is a marker of subclinical abnormalities in cardiac structure and function, with abnormal parameters correlating with reduced ejection fraction and increased LV mass and volumes.
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May flag subclinical LV remodeling on routine ECG; hypothesis-generating for outcome prediction and risk stratification.
Biering‐Sørensen et al. (2018) conducted a cohort in General population (n=14,609). Abnormal global electric heterogeneity (GEH) was evaluated on Left ventricular ejection fraction decline (6.4% decline, 95% CI 5.5-7.3). Having 4 abnormal global electric heterogeneity parameters was associated with a 6.4% (95% CI, 5.5-7.3) decline in left ventricular ejection fraction and increases in LV mass and volumes.
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