Key result
A biophysical model of cardiac electrical activity incorporating electrophysiological and anatomical characteristics was developed and integrated into a computer modeling system.
Describes the development and integration of a biophysical computer model of cardiac ventricular electrical activity for simulating electrocardiosignals.
Some principles for the realization of biophysical models of electrical activity of heart ventricles, presented by a double electrical layer along the surface of the electrically active myocardium and the boundary surfaces that divide model compartments with different electrophysiological properties, have been considered. The parameters of the model are the electrophysiological and anatomical characteristics of the heart, such as the geometry of ventricles and the His-Purkinje specialized conductive system, the velocity of depolarization propagation in the myocardium, the ratio of excitation velocities in "Myocardium", "His", and "Purkinje" model elements, the ,shape of transmembrane action potentials on boundary surfaces, the orientation of the own heart anatomical axes relative to the initial coordinate system, and others. The model has been included as a basic unit into a computer modeling system containing databases of simulated and real electrocardiosignals.
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Baum et al. (2009) studied Cardiac electrical activity. Biophysical models of cardiac electrical activity was evaluated. A biophysical model of cardiac electrical activity incorporating electrophysiological and anatomical characteristics was developed and integrated into a computer modeling system.
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