Key result
NFκB serves as a key functional link in the crosstalk between inflammation and cardiovascular diseases, representing a potential therapeutic target for the failing heart.
Why the study?
Inflammation contributes significantly to cardiovascular diseases, and NFkappaB represents a key functional link in the crosstalk between inflammation and cardiac and vascular damage.
NFκB is a key functional link between inflammation and cardiovascular diseases, representing a potential therapeutic target for heart failure.
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No immediate clinical application in heart failure; leaves open NFκB-targeted therapies for prospective trials.
Fiordelisi et al. (2019) conducted a review in Cardiovascular diseases and inflammation. Therapeutic targeting of NFκB was evaluated. NFκB serves as a key functional link in the crosstalk between inflammation and cardiovascular diseases, representing a potential therapeutic target for the failing heart.
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