Key result
A computer model of human atria demonstrated that single-site burst pacing induces wave breaks and that reducing action potential duration increases the duration of atrial fibrillation.
Population
Computer model of human atria derived from a segmented magnetic resonance imaging data set, using an…
Design
Preclinical
Authors
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Should not change AF management; leaves open whether APD reduction promotes arrhythmia persistence in patients.
A 3D computer model of human atria demonstrates that reduced action potential duration increases the duration of simulated atrial fibrillation.
Virag et al. (2002) studied Atrial fibrillation. Computer model of human atria was evaluated on Initiation and perpetuation of multiple wavelets. A computer model of human atria demonstrated that single-site burst pacing induces wave breaks and that reducing action potential duration increases the duration of atrial fibrillation.
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