Key result
A realistic 3D computer model of the human atria demonstrated that complex fractionated atrial electrograms are associated with pivot points of rotors, while double potentials relate to wave fragmentations or blocking lines.
A novel 3D human atrial computational model demonstrates that stable arrhythmic activity produces simple electrograms, whereas unstable activity during atrial fibrillation generates polymorphic and fragmented potentials.
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Model links CFAEs to rotor pivots in AF; leaves open whether targeting them improves ablation outcomes.
Tobón et al. (2013) studied Atrial fibrillation and atrial tachyarrhythmias. 3D computer model of human atria was evaluated on Relationship between electrogram characteristics and arrhythmic propagation patterns. A realistic 3D computer model of the human atria demonstrated that complex fractionated atrial electrograms are associated with pivot points of rotors, while double potentials relate to wave fragmentations or blocking lines.
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