Why the study?
Do myocardial regions with exercise-induced ischemia exhibit structural alterations compared to normally contracting regions?
Do myocardial regions with exercise-induced ischemia exhibit structural alterations compared to normally contracting regions?
Transiently ischemic myocardium with normal resting function develops structural alterations, including muscle fiber hypertrophy and increased interstitial nonmuscular tissue, particularly in the endocardial layers.
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Exercise-induced ischemia links to hypertrophy and interstitial expansion; hypothesis-generating and requires prospective confirmation before clinical relevance.
Hess et al. (1988) studied this question.
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