Key result
Programming pacemakers to 60 bpm in ICD patients with prior pacemaker-induced tachycardias led to recurrence in 83.3% (5 of 6), whereas 0% had recurrences when the pacemaker was turned off.
Why the study?
Does right ventricular VVI backup pacing at 60 bpm induce pacemaker-induced tachycardias in patients with implanted cardioverter-defibrillators compared to turning the pacemaker off?
Population
13 patients with implanted cardioverter-defibrillators presenting exclusively with pacemaker-induced…
Comparison
Right ventricular VVI backup pacing with… vs Pacemaker turned off.
Design
RCT, Randomized to either group 1 or group 2 in a crossover protocol.
Follow-up
1 year per crossover phase
Authors
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Disable VVI backup pacing at 60 bpm in affected ICD patients; confirms it induces tachycardias absent primary indication.
RCT (n=13)
Crossover
Does right ventricular VVI backup pacing at 60 bpm induce pacemaker-induced tachycardias in patients with implanted cardioverter-defibrillators compared to turning the pacemaker off?
Absolute Event Rate: 83.3% vs 0%
In ICD patients experiencing pacemaker-induced tachycardias without a primary pacing indication, turning off the backup pacing feature effectively eliminates these proarrhythmic events.
Himmrich et al. (2003) conducted an RCT in Implanted cardioverter-defibrillators with pacemaker-induced tachycardias (n=13). Pacemaker programmed to 60 bpm vs. Pacemaker turned off was evaluated on Recurrence of pacemaker-induced tachycardia (PIT). Programming pacemakers to 60 bpm in ICD patients with prior pacemaker-induced tachycardias led to recurrence in 83.3% (5 of 6), whereas 0% had recurrences when the pacemaker was turned off.
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