Why the study?
Do patients with primary congestive and hypertrophic cardiomyopathies have a higher frequency of circulating heart reactive antibodies compared to controls?
Population
Patients with primary congestive and hypertrophic cardiomyopathies and other heart diseases, and controls
Comparison
Standard 'single sandwich' and 'double sandwich'… vs Controls
Design
Case-control
Authors
Loading...
Questions immunofluorescence detection of heart antibodies in cardiomyopathies; challenges prior associations and leaves role of autoantibodies open.
Do patients with primary congestive and hypertrophic cardiomyopathies have a higher frequency of circulating heart reactive antibodies compared to controls?
Indirect immunofluorescence techniques failed to show a significant difference in circulating heart reactive antibodies between cardiomyopathy patients and controls, highlighting significant method-specific artifacts and observer variation.
Trueman et al. (1981) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: