Why the study?
Does the assay of circulating heart-reactive antibody predict cardiac rejection in patients with cardiac allografts?
Population
3 patients with cardiac transplants
Design
Case_series
Authors
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May signal early rejection in heart transplant recipients; hypothesis-generating and requires prospective validation before clinical adoption.
Does the assay of circulating heart-reactive antibody predict cardiac rejection in patients with cardiac allografts?
Assay of heart-reactive antibody may serve as an early and sensitive indicator of cardiac rejection in heart transplant recipients before significant cardiac dysfunction occurs.
Robert J. Ellis (1970) studied this question.
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