Why the study?
How do additional valve lesions affect left ventricular ejection time in patients with aortic stenosis?
Population
171 catheterised patients with aortic valve area ≤ 1.2 cm2 and 13 normal subjects
Comparison
Presence of additional valve lesions vs Pure aortic stenosis or normal subjects
Design
Cross-sectional
Authors
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Coexisting mitral lesions may mask LVET prolongation in aortic stenosis; leaves open its utility as an isolated severity marker.
How do additional valve lesions affect left ventricular ejection time in patients with aortic stenosis?
Prolonged left ventricular ejection time in aortic stenosis is further increased by aortic regurgitation but may be pseudo-normalized by coexisting significant mitral stenosis or severe mitral regurgitation.
Kligfield et al. (1977) studied this question.
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