Key result
Dual-energy lattice-tip ablation successfully and safely treats complex arrhythmias in adult congenital heart disease.
Why the study?
Arrhythmia ablation in patients with adult congenital heart disease is challenging due to complex anatomy and previous surgical repair, but novel catheters combining 3D mapping with pulsed-field and radiofrequency ablation may streamline procedures.
Does dual-energy lattice-tip catheter ablation (combining pulsed-field and radiofrequency energy) successfully treat atrial and ventricular arrhythmias in adult patients with congenital heart disease?
Case Report (n=5)
Does dual-energy lattice-tip catheter ablation (combining pulsed-field and radiofrequency energy) successfully treat atrial and ventricular arrhythmias in adult patients with congenital heart disease?
A dual-energy lattice-tip catheter provides an efficient and versatile method for mapping and ablating both atrial and ventricular arrhythmias in patients with complex adult congenital heart disease.
May enable single-session ablation of atrial and ventricular arrhythmias in adult congenital heart disease; extends prior techniques but remains hypothesis-generating.
BACKGROUND: Patients with adult congenital heart disease (ACHD) often develop atrial and ventricular arrhythmias. Ablation is challenging given complex anatomy and previous surgical repair. Pulsed-field ablation (PFA) offers improved efficacy and safety through myocardial selectivity. Novel catheters combining three-dimensional electroanatomical mapping with both PFA and radiofrequency ablation (RFA) streamline procedures in ACHD patients. METHODS: We present a case series of 5 ACHD patients with symptomatic atrial and/or ventricular arrhythmias who underwent ablation using a dual-energy "map-and-ablate" lattice-tip catheter. RESULTS: Using the lattice-tip catheter, pulmonary vein isolation, cavotricuspid isthmus ablation, and ablation of scar-related intra-atrial re-entry with combined RFA and PFA were performed in 2 patients and ablation of re-entrant ventricular arrhythmias in 3 patients. In 2 patients, both atrial and ventricular arrhythmias were ablated in the same procedure. CONCLUSIONS: Use of a large-area focal ablation catheter with mapping integration and dual-energy capabilities enables efficient and safe atrial and ventricular arrhythmia ablation in patients with ACHD.
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Iqbal et al. (2025) conducted a case report in Complex adult congenital heart disease with symptomatic atrial and/or ventricular arrhythmias (n=5). Dual-energy lattice-tip map-and-ablate catheter (Sphere-9) ablation was evaluated on Successful ablation of targeted arrhythmias and acute freedom from inducibility. A dual-energy, lattice-tip, map-and-ablate catheter combining radiofrequency and pulsed-field ablation safely and effectively treated complex atrial and ventricular arrhythmias in 5 patients with adult congenital heart disease.
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