Key result
Intracardiac ARFI imaging provided significantly higher lesion contrast-to-noise ratio (1.83 ± 1.75) than conventional B-mode images (0.74 ± 0.68) for identifying ablation lesions.
Why the study?
Does intracardiac ARFI imaging provide better contrast and visualization of radiofrequency ablation lesions compared to conventional intracardiac echo in a canine model?
Does intracardiac ARFI imaging provide better contrast and visualization of radiofrequency ablation lesions compared to conventional intracardiac echo in a canine model?
Absolute Event Rate: 1.83% vs 0.74%
Intracardiac ARFI imaging provides superior contrast and visualization of radiofrequency ablation lesions compared to conventional B-mode echocardiography in a preclinical model.
Should not yet change ablation imaging practice; extends preclinical evidence for ARFI lesion visualization.
We have previously shown that intracardiac acoustic radiation force impulse (ARFI) imaging visualizes tissue stiffness changes caused by radiofrequency ablation (RFA). The objectives of this in vivo study were to (1) quantify measured ARFI-induced displacements in RFA lesion and unablated myocardium and (2) calculate the lesion contrast (C) and contrast-to-noise ratio (CNR) in two-dimensional ARFI and conventional intracardiac echo images. In eight canine subjects, an ARFI imaging-electroanatomical mapping system was used to map right atrial ablation lesion sites and guide the acquisition of ARFI images at these sites before and after ablation. Readers of the ARFI images identified lesion sites with high sensitivity (90.2%) and specificity (94.3%) and the average measured ARFI-induced displacements were higher at unablated sites (11.23 ± 1.71 µm) than at ablated sites (6.06 ± 0.94 µm). The average lesion C (0.29 ± 0.33) and CNR (1.83 ± 1.75) were significantly higher for ARFI images than for spatially registered conventional B-mode images (C = -0.03 ± 0.28, CNR = 0.74 ± 0.68).
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Eyerly‐Webb et al. (2014) studied Radiofrequency ablation lesions (n=8). Intracardiac acoustic radiation force impulse (ARFI) imaging vs. Conventional intracardiac echo (B-mode) images was evaluated on Lesion contrast-to-noise ratio (CNR). Intracardiac ARFI imaging provided significantly higher lesion contrast-to-noise ratio (1.83 ± 1.75) than conventional B-mode images (0.74 ± 0.68) for identifying ablation lesions.
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