Key result
HNK-1 immunohistochemistry in human embryos showed that left and right atrial pacemaker foci correspond to areas of the embryonic myocardium that temporarily express the HNK-1 antigen.
Observational
Ectopic pacemaker sites in patients with abnormal atrial automaticity correspond to areas of embryonic myocardium that temporarily express the HNK-1 antigen.
No takes yet. Share an insight, caveat, or question.
May explain ectopic atrial pacemaker sites in young patients; extends embryonic mapping but leaves open clinical translation.
Blom et al. (1999) conducted an observational in Cardiac conduction system development. HNK-1 immunohistochemistry was evaluated on HNK-1 antigen expression in the developing cardiac conduction system. HNK-1 immunohistochemistry in human embryos showed that left and right atrial pacemaker foci correspond to areas of the embryonic myocardium that temporarily express the HNK-1 antigen.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: