Key result
More extensive ablation lesions (28 ± 8 vs. 12 ± 8 lesions; P=0.01) and linear rather than focal lesions (P=0.03) were associated with better long-term success in scar-related VT ablation.
Why the study?
Does the extent and type of ablation lesions (linear vs focal) predict long-term success and recurrence in patients with large scar-related ventricular tachycardia?
Observational
Does the extent and type of ablation lesions (linear vs focal) predict long-term success and recurrence in patients with large scar-related ventricular tachycardia?
p-value: p=0.01
More extensive and linear ablation lesions are associated with higher long-term success and lower recurrence rates in patients undergoing ablation for large scar-related ventricular tachycardia.
Hypothesis-generating for lesion strategy in scar-related VT; prospective randomized trials needed before clinical adoption.
During ablation of re-entrant ventricular tachycardia (VT) 3-dimensional mapping systems are now used to properly delineate the scar tissue and aid ablation of scar-related VT. The aim of our study was to outline how the mode of ablation predicts success and recurrence in large scar-related VT. When comparing patients with recurrence and patients with no recurrence, univariate analysis showed that number of ablation lesions (28 ± 8 vs. 12 ± 8, P = 0.01) and more linear ablation lesions rather than focal lesions (P = 0.03) were associated with long-term success. We demonstrated that more extensive ablation lesions and creation of linear lesions is associated with better success rate and lower recurrence rate during ablation of large scar-related ventricular tachycardia.
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Ghanem et al. (2013) conducted an observational in Scar-related ventricular tachycardia. Extensive and linear ablation lesions vs. Fewer and focal ablation lesions was evaluated on Long-term success and recurrence (p=0.01). More extensive ablation lesions (28 ± 8 vs. 12 ± 8 lesions; P=0.01) and linear rather than focal lesions (P=0.03) were associated with better long-term success in scar-related VT ablation.
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