Key result
DeltaFEV1 (r=0.50), dynamic hyperinflation index (r=0.50), and ventilatory response to exercise (r=0.46) correlated significantly with peak VO2 in COPD patients, exceeding the impact of FEV1.
Observational (n=24)
Effect estimate: r = 0.50
Variability in ventilatory response to exercise and deltaFEV1 contribute importantly to exercise tolerance in COPD patients.
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Should not yet change COPD exercise assessment; hypothesis-generating for ventilatory factors beyond FEV1.
Bauerle et al. (1998) conducted an observational in COPD (n=24). Symptom-limited progressive exercise testing was evaluated on Peak VO2 (r = 0.50). DeltaFEV1 (r=0.50), dynamic hyperinflation index (r=0.50), and ventilatory response to exercise (r=0.46) correlated significantly with peak VO2 in COPD patients, exceeding the impact of FEV1.
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