Why the study?
It was unknown whether central hemodynamics are impaired during exercise in patients with chronic obstructive pulmonary disease.
Do patients with COPD have impaired central hemodynamics (cardiac output and stroke volume) during submaximal exercise compared to healthy controls?
Population
13 clinically stable COPD patients and 10 controls
Comparison
COPD patients vs healthy controls during constant workload submaximal exercise
Design
Physiological cross-sectional study
Authors
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May link hyperinflation to blunted exercise hemodynamics in COPD; leaves open whether volume-targeted interventions improve cardiac output.
Do patients with COPD have impaired central hemodynamics (cardiac output and stroke volume) during submaximal exercise compared to healthy controls?
Patients with COPD exhibit impaired central hemodynamics (reduced cardiac output and stroke volume) during submaximal exercise, which correlates with the severity of static hyperinflation.
Smith et al. (2019) studied this question.