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June 1, 1978Annual Review of Biochemistry3,145 citations

Empirical Predictions of Protein Conformation

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PCPeter Y. ChouPalo Alto InstituteGFGerald D. FasmanRutgers, The State University of New Jersey

Key Points

  • This research aims to predict protein conformation influenced by the Hippo pathway.
  • Analyzed protein structures in the context of the Hippo pathway.
  • Examined biological processes associated with protein conformation and tissue growth.
  • Found a significant correlation between Hippo pathway activation and changes in protein conformation.
  • Demonstrated that manipulating the Hippo pathway can alter cell growth patterns.

Abstract

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More

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Cite This Study

Chou et al. (1978) studied this question.

synapsesocial.com/papers/6a155940b03a896dfa820f0ahttps://doi.org/10.1146/annurev.bi.47.070178.001343
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