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Review highlights evolutionary conservation of the Hippo signaling cascade in biological systems, suggesting fundamental roles in controlling organ size and cell fate.
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...
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Hans J. Müller‐Eberhard (1975) studied this question.
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