Key result
Failure to terminate AF during index ablation predicted atrial tachyarrhythmia recurrence compared to termination at the PV antrum (HR 2.32; 95% CI 1.26-6.30; P=0.023).
Why the study?
Does the site and mode of atrial fibrillation termination during index catheter ablation predict atrial tachyarrhythmia recurrence in patients with persistent atrial fibrillation?
Cohort (n=135)
Does the site and mode of atrial fibrillation termination during index catheter ablation predict atrial tachyarrhythmia recurrence in patients with persistent atrial fibrillation?
Effect estimate: HR 2.32 (95% CI 1.26-6.30)
p-value: p=0.023
In patients undergoing catheter ablation for persistent atrial fibrillation, termination of AF at the pulmonary vein antrum and direct conversion to sinus rhythm are independent predictors of lower long-term arrhythmia recurrence.
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AF termination at PV antrum may indicate lower recurrence risk after persistent AF ablation; leaves open whether targeting it improves outcomes.
Miyazaki et al. (2013) conducted a cohort in Persistent atrial fibrillation (PsAF) (n=135). Catheter ablation vs. AF termination at pulmonary vein antrum or sinus rhythm was evaluated on Atrial tachyarrhythmia (ATa) recurrence (HR 2.32, 95% CI 1.26-6.30, p=0.023). Failure to terminate AF during index ablation predicted atrial tachyarrhythmia recurrence compared to termination at the PV antrum (HR 2.32; 95% CI 1.26-6.30; P=0.023).
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