Key result
Eccentric LV hypertrophy affects 36% of hypertensive OSA patients and is linked to lower LVEF.
Why the study?
The study was conducted to compare polygraphic parameters and selected laboratory parameters in patients with obstructive sleep apnoea who develop various types of left ventricular geometry.
What are the clinical, polygraphic, and laboratory characteristics associated with different types of left ventricular geometry in hypertensive patients with obstructive sleep apnea?
Cross-Sectional (n=122)
What are the clinical, polygraphic, and laboratory characteristics associated with different types of left ventricular geometry in hypertensive patients with obstructive sleep apnea?
p-value: p=0.0008
In hypertensive patients with obstructive sleep apnea, eccentric hypertrophy is the most common left ventricular geometry and is associated with significantly decreased left ventricular ejection fraction.
Objective . The objective of the study was to compare polygraphic parameters and selected laboratory parameters in patients with obstructive sleep apnoea (OSA) who develop various types of left ventricular (LV) geometry. Material and Methods . The research covered 122 patients with obstructive sleep apnoea and coexisting effectively treated systemic hypertension (95 men, 27 women, average age: 54 ± 10.63). Overnight polygraphy, echocardiography, carotid artery ultrasonography, and laboratory measurements were performed. The patients were classified into four groups, depending on LV geometry. Group 1 comprised patients with normal LV geometry, group 2 included those with LV concentric remodelling. Group 3 and group 4 were patients with LV hypertrophy, concentric or eccentric, respectively. Results . The most frequent type of LV geometry in the examined population was eccentric hypertrophy (36%). The highest average values of BMI and T‐Ch were observed in the group of patients with concentric remodelling (group 2). The most severe respiratory disorders were found in the group of patients developing LV concentric hypertrophy (group 3); however, these differences were not statistically significant in comparison to other groups. Patients with LV eccentric hypertrophy had significantly decreased LV ejection fraction ( p = 0.0008). Conclusions . LV eccentric hypertrophy is the most frequent type of LV geometry in OSA patients. Patients with severe sleep‐disordered breathing are more likely to develop concentric hypertrophy, while concentric remodelling occurs more frequently among OSA patients with other coexisting conditions, such as obesity or lipid‐related disorders.
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Myśliński et al. (2021) conducted a cross-sectional in Obstructive sleep apnoea and systemic hypertension (n=122). Left ventricular geometry classification vs. Comparison among normal geometry, concentric remodelling, concentric hypertrophy, and eccentric hypertrophy was evaluated on Left ventricular geometry distribution and associated clinical parameters (p=0.0008). In patients with obstructive sleep apnoea and hypertension, eccentric hypertrophy was the most frequent left ventricular geometry (36%) and was associated with significantly decreased ejection fraction (p=0.0008).
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