Key result
Moderate/severe obstructive sleep apnea was associated with a significantly higher prevalence of concentric left ventricular geometry compared to controls (58% vs 20%; OR 7.6, P<0.001).
Why the study?
Does moderate/severe obstructive sleep apnea increase the prevalence of concentric left ventricular geometry in patients with suspected OSA?
Cross-Sectional (n=157)
Does moderate/severe obstructive sleep apnea increase the prevalence of concentric left ventricular geometry in patients with suspected OSA?
Effect estimate: OR 7.6
Absolute Event Rate: 58% vs 20%
p-value: p=< 0.001
Moderate to severe obstructive sleep apnea is strongly associated with concentric left ventricular geometry, which may contribute to the increased rate of cardiovascular events in this population.
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May warrant echocardiography in moderate/severe OSA; leaves open causality and treatment effects on geometry.
Cioffi et al. (2010) conducted a cross-sectional in Suspected obstructive sleep apnea (n=157). Moderate/severe obstructive sleep apnea vs. Controls and mild obstructive sleep apnea was evaluated on Concentric left ventricular geometry (OR 7.6, p=< 0.001). Moderate/severe obstructive sleep apnea was associated with a significantly higher prevalence of concentric left ventricular geometry compared to controls (58% vs 20%; OR 7.6, P<0.001).
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