Abnormal right ventricular mechanics in early systemic hypertension: a two-dimensional strain imaging study
Key result
Increasing 24-hour systolic blood pressure (≥117 mmHg) was associated with decreased right ventricular peak systolic strain and early diastolic strain rate compared to optimal blood pressure.
Why the study?
Does increasing systemic blood pressure affect right ventricular mechanics and function as assessed by two-dimensional strain imaging in never-treated, non-obese subjects?
Population
89 never-treated, non-obese subjects with office blood pressure values varying from the optimal to mildly…
Design
Cross-sectional
Authors
Discussion
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Implication
RV strain abnormalities below hypertension thresholds may signal early risk; hypothesis-generating and requires longitudinal confirmation before clinical use.
Study Design
Type
Cross-Sectional (n=89)
Structured PICO
Does increasing systemic blood pressure affect right ventricular mechanics and function as assessed by two-dimensional strain imaging in never-treated, non-obese subjects?
P
Population
89 never-treated, non-obese subjects with office blood pressure values varying from the optimal to mildly hypertensive range.
O
Outcome
Right ventricular (RV) function (longitudinal peak strain and strain rate at the RV free wall and interventricular septum) assessed by two-dimensional strain imagingsurrogate
Subclinical right ventricular systolic and diastolic abnormalities are detectable by 2D strain imaging even at blood pressure levels below the conventional diagnostic limits for hypertension.
Cite This Study
Pedrinelli et al. (2010) conducted a cross-sectional in Early systemic hypertension (n=89). Increasing systemic blood pressure vs. Optimal blood pressure (<117 mmHg) was evaluated on Right ventricular longitudinal peak strain and strain rate. Increasing 24-hour systolic blood pressure (≥117 mmHg) was associated with decreased right ventricular peak systolic strain and early diastolic strain rate compared to optimal blood pressure.