Key result
Neglecting cardiac electrical anisotropy in noninvasive activation time imaging had small effects on inverse solutions, yielding a worst-case correlation coefficient of 0.810 for estimated maps.
Why the study?
Does neglecting cardiac anisotropy affect the accuracy of noninvasive activation time imaging?
Does neglecting cardiac anisotropy affect the accuracy of noninvasive activation time imaging?
Effect estimate: Correlation coefficient 0.810
Cardiac anisotropy may be negligible for certain clinical applications of noninvasive activation time imaging, as key activation events can still be accurately estimated.
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Neglecting anisotropy yields acceptable accuracy in animal models; leaves open need for human validation before clinical use.
Modre et al. (2006) studied Ventricular depolarization. Noninvasive activation time imaging neglecting cardiac anisotropy vs. Anisotropic conditions was evaluated on Correlation coefficient of estimated activation time maps (Correlation coefficient 0.810). Neglecting cardiac electrical anisotropy in noninvasive activation time imaging had small effects on inverse solutions, yielding a worst-case correlation coefficient of 0.810 for estimated maps.
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