Key result
Anisotropic computer heart models showed no significant differences compared to isotropic models in excitation processes or surface ECGs, but ventricular fibrillation was easier to induce.
Why the study?
Does an anisotropic computer heart model differ from an isotropic model in simulating the excitation process and body surface electrocardiogram?
Does an anisotropic computer heart model differ from an isotropic model in simulating the excitation process and body surface electrocardiogram?
Anisotropic computer heart models do not significantly alter simulated normal or bundle branch block ECGs compared to isotropic models, but they facilitate the induction of ventricular fibrillation.
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Isotropic models suffice for ECG simulation; leaves open anisotropy effects on VF inducibility in computational studies.
Wei et al. (1995) studied Normal heart, LBBB, RBBB, ventricular fibrillation. Anisotropic computer heart model vs. Isotropic computer heart model was evaluated on Excitation process of the heart and body surface electrocardiogram. Anisotropic computer heart models showed no significant differences compared to isotropic models in excitation processes or surface ECGs, but ventricular fibrillation was easier to induce.
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