Key result
Moderate/severe cognitive impairment was independently associated with higher in-hospital mortality in older patients with STEMI (OR 2.2; 95% CI 1.8-2.7) and NSTEMI (OR 1.7; 95% CI 1.4-2.0).
Why the study?
Little was known regarding the use of cardiac therapies and clinical outcomes among older myocardial infarction patients with cognitive impairment.
Does cognitive impairment increase in-hospital mortality and alter treatment patterns in older patients with myocardial infarction?
Cohort (n=134,716)
Yes
Does cognitive impairment increase in-hospital mortality and alter treatment patterns in older patients with myocardial infarction?
Effect estimate: OR 2.2 (95% CI 1.8-2.7)
Cognitive impairment in older MI patients is associated with less invasive care in NSTEMI and higher in-hospital mortality across both STEMI and NSTEMI.
No takes yet. Share an insight, caveat, or question.
May flag higher mortality risk in older MI patients; hypothesis-generating for whether cognitive status should influence care.
Bagai et al. (2019) conducted a cohort in Myocardial infarction with cognitive impairment (n=134,716). Cognitive impairment vs. No cognitive impairment was evaluated on all-cause in-hospital mortality (OR 2.2, 95% CI 1.8-2.7). Moderate/severe cognitive impairment was independently associated with higher in-hospital mortality in older patients with STEMI (OR 2.2; 95% CI 1.8-2.7) and NSTEMI (OR 1.7; 95% CI 1.4-2.0).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: