Key result
Baseline depression in older adults undergoing TAVR or SAVR was associated with increased all-cause mortality at 1 month (OR 2.20) and 12 months (OR 1.532; 95% CI 1.03-2.24).
Why the study?
Does depression increase all-cause mortality in older adults undergoing TAVR or SAVR?
Cohort (n=1,035)
Yes
Does depression increase all-cause mortality in older adults undergoing TAVR or SAVR?
Effect estimate: OR 1.532 (95% CI 1.03-2.24)
Depressive symptoms are present in nearly one-third of older adults undergoing TAVR or SAVR and are associated with a significantly increased risk of short- and mid-term mortality.
No takes yet. Share an insight, caveat, or question.
Depression signals higher short-term mortality risk after TAVR/SAVR; hypothesis-generating for screening or intervention trials.
Drudi et al. (2018) conducted a cohort in older adults undergoing transcatheter (TAVR) or surgical (SAVR) aortic valve replacement (n=1,035). Baseline depression vs. No baseline depression was evaluated on All-cause mortality at 12 months (OR 1.532, 95% CI 1.03-2.24). Baseline depression in older adults undergoing TAVR or SAVR was associated with increased all-cause mortality at 1 month (OR 2.20) and 12 months (OR 1.532; 95% CI 1.03-2.24).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: