Key result
Higher 24-h aortic pulse pressure is strongly associated with reduced choroidal thickness in hypertensive patients.
Why the study?
Controversy exists regarding the association of choroidal thickness with blood pressure values, while evidence suggests central hemodynamic changes relate to microvascular disease.
Cross-Sectional (n=158)
Effect estimate: r = -0.531
p-value: p=<.001
Higher 24-hour aortic pulse pressure is significantly associated with reduced choroidal thickness in hypertensive patients, supporting a link between macro- and microcirculation.
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Association between aortic pulse pressure and choroidal thickness is hypothesis-generating; leaves open whether macrovascular changes affect ocular microcirculation in hypertension.
Mulè et al. (2021) conducted a cross-sectional in Essential hypertension (n=158). 24-h aortic pulse pressure (aPP) vs. Lower 24-h aPP (below median 35 mm Hg) was evaluated on Correlation between 24-h aPP and overall average choroidal thickness (r = -0.531, p=<.001). Higher 24-h aortic pulse pressure was significantly inversely correlated with overall average choroidal thickness in hypertensive patients (r = -0.531; P < .001).
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