Similar pattern of change in Vo2kinetics, vascular function, and tissue oxygen provision following an endurance training stimulus in older and young adults
Key result
Endurance cycling training significantly reduced the time constant of V̇o2 at 24 h posttraining in older (~18%) and young (~23%) men (P<0.001), returning toward pretraining values by 120 h.
Why the study?
Does short-term endurance cycling exercise training improve oxygen uptake kinetics and vascular function in healthy older and young men?
Population
Healthy older men (mean age 74 ± 6 years) and young men (mean age 25 ± 3 years)
Comparison
Three endurance cycling exercise training… vs Pretraining (baseline) values
Design
Cohort
Follow-up
120 hours posttraining
Authors
Discussion
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Implication
Supports transient, age-independent VO2 kinetics gains after short-term training; leaves open causal effects and clinical relevance pending RCTs.
Structured PICO
Does short-term endurance cycling exercise training improve oxygen uptake kinetics and vascular function in healthy older and young men?
P
Population
Healthy older men (mean age 74 ± 6 years) and young men (mean age 25 ± 3 years)
I
Intervention
Three endurance cycling exercise training sessions at 70% V̇o2peak
C
Comparator
Pretraining (baseline) values
O
Outcome
Time course of changes in oxygen uptake (V̇o2) kinetics response at 24, 48, 72, and 120 hours posttrainingsurrogate
Main Result
p-value: p=<0.001
Short-term endurance training induces similar temporal improvements in V̇o2 kinetics and vascular function in both young and older men, suggesting oxygen availability constrains the rate of V̇o2 adjustment.
Cite This Study
McLay et al. (2017) studied Healthy. Endurance cycling exercise training vs. Pretraining baseline was evaluated on Time constant of V̇o2 (τV̇o2) at 24 hours posttraining (p=<0.001). Endurance cycling training significantly reduced the time constant of V̇o2 at 24 h posttraining in older (~18%) and young (~23%) men (P<0.001), returning toward pretraining values by 120 h.