Key result
Adequate oxygen provision to active tissues is critical in the dynamic adjustment of oxidative phosphorylation during the exercise on-transient, even in young healthy individuals.
Why the study?
Does adequate O2 provision play a critical role in the dynamic adjustment of oxidative phosphorylation during the exercise on-transient in young healthy individuals?
Does adequate O2 provision play a critical role in the dynamic adjustment of oxidative phosphorylation during the exercise on-transient in young healthy individuals?
This review highlights that muscle oxygen delivery is a critical rate-limiting factor for oxidative phosphorylation during exercise onset, even in young healthy individuals.
Supports reevaluating O2 delivery assumptions during exercise onset; leaves open effects of targeted interventions on performance.
In Brief It has been proposed that the adjustment of oxygen uptake (V˙O2) during the exercise on-transient is controlled intracellularly in young healthy individuals and that insufficient local O2 delivery plays a rate-limiting role in aging and disease only. This review shows that adequate O2 provision to the active tissues is critical in the dynamic adjustment of oxidative phosphorylation even in young healthy individuals. This review illustrates the critical role of muscle oxygen delivery in the adjustment of oxidative phosphorylation during the exercise on-transient.
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Murias et al. (2013) conducted a review in Exercise physiology. Oxygen provision was evaluated on Adjustment of oxidative phosphorylation. Adequate oxygen provision to active tissues is critical in the dynamic adjustment of oxidative phosphorylation during the exercise on-transient, even in young healthy individuals.
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