Key result
Daily injection of human leukocyte interferon for 1 week lowered plasma cholesterol levels and decreased the activity of postheparin plasma hepatic and lipoprotein lipases by 20% to 50%.
Why the study?
Does daily injection of human leukocyte interferon alter plasma lipoproteins and lipase activity in healthy men?
Observational (n=6)
Does daily injection of human leukocyte interferon alter plasma lipoproteins and lipase activity in healthy men?
Interferon administration lowers plasma lipoproteins and decreases lipase activity, highlighting a potential mechanism for lipid changes seen in acute and chronic infections.
No takes yet. Share an insight, caveat, or question.
No immediate practice change; leaves open interferon modulation of lipoproteins in infection.
Ehnholm et al. (1982) conducted an observational in Healthy (n=6). Human leukocyte interferon was evaluated on Concentration of plasma lipoproteins and activity of postheparin plasma lipases. Daily injection of human leukocyte interferon for 1 week lowered plasma cholesterol levels and decreased the activity of postheparin plasma hepatic and lipoprotein lipases by 20% to 50%.
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