Key result
Reducing the phase angle between pressure and flow from -60 to -80 degrees in an elastic tube model resulted in a fivefold increase in peak wall shear stress and intense shear stress reversal.
In an elastic tube model of the aorta, reducing the phase angle between pressure and flow from -60 to -80 degrees significantly increases peak wall shear stress, which may have implications for atherogenesis in conditions like hypertension.
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Phase angle reduction may promote atherogenesis via elevated shear stress; leaves open translation from tube models to clinical hypertension.
Klanchar et al. (1990) studied this question. Changing the distal impedance element (phase angle between pressure and flow) was evaluated on Wall shear stress. Reducing the phase angle between pressure and flow from -60 to -80 degrees in an elastic tube model resulted in a fivefold increase in peak wall shear stress and intense shear stress reversal.
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