Key result
High density binding of angiotensin-II receptors was found in mesenchymal tissue throughout the primate fetus body, with a single class of sites showing a Kd of 0.6 +/- 0.1 nM.
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May indicate developmental role for angiotensin-II in fetal growth; leaves open functional and clinical implications for RAS modulation.
Zemel et al. (1990) studied Angiotensin-II Receptors in Primate Fetus. Angiotensin-II (AII) receptors characterization vs. Adult monkey/human tissues was evaluated on Binding characteristics and distribution of angiotensin-II (AII) receptors. High density binding of angiotensin-II receptors was found in mesenchymal tissue throughout the primate fetus body, with a single class of sites showing a Kd of 0.6 +/- 0.1 nM.
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