Key result
Smoking was associated with significantly higher peripheral Pulse Wave Velocity (5.7±0.5 m/s vs 4.8±0.4 m/s; p<0.001) and increased intrinsic sympathetic activity compared to non-smokers.
Why the study?
Does smoking increase peripheral arterial stiffness and alter autonomic functions in adult males?
Population
100 adult males (20-40 years), comprising 50 smokers and 50 non-smokers.
Comparison
Smoking (exposure) vs Non-smokers
Design
Cross-sectional
Authors
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Supports smoking-related vascular risk awareness in males; hypothesis-generating and requires longitudinal confirmation before practice change.
Cross-Sectional (n=100)
No
Does smoking increase peripheral arterial stiffness and alter autonomic functions in adult males?
Absolute Event Rate: 5.7% vs 4.8%
p-value: p=<0.001
Smoking is associated with increased peripheral arterial stiffness and altered autonomic function, characterized by increased sympathetic and decreased parasympathetic activity, in adult males.
Sukhmani Saini (2016) conducted a cross-sectional in Smoking (n=100). Smoking vs. Non-smokers was evaluated on Pulse Wave Velocity (PWV) (p=<0.001). Smoking was associated with significantly higher peripheral Pulse Wave Velocity (5.7±0.5 m/s vs 4.8±0.4 m/s; p<0.001) and increased intrinsic sympathetic activity compared to non-smokers.
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