Key result
Chronic tobacco smoking was associated with a significantly higher systemic augmentation index compared to nonsmokers (median 17.25% vs 11.75%, P=0.004).
Why the study?
Does smoking cessation improve arterial stiffness (AIx and PWV) in chronic smokers?
Population
120 subjects total: 50 smokers and 50 age- and sex-matched nonsmokers, and 20 volunteers from a stop smoking…
Comparison
Smoking cessation / Chronic tobacco smoking vs Nonsmokers (Study 1) / Relapsed smokers (Study 2)
Design
Cohort
Follow-up
4 weeks (Study 2)
Authors
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Supports smoking cessation counseling to potentially reduce arterial stiffness; leaves open reversibility of augmentation index in prospective trials.
Observational (n=120)
No
Does smoking cessation improve arterial stiffness (AIx and PWV) in chronic smokers?
Absolute Event Rate: 17.25% vs 11.75%
p-value: p=0.004
Chronic smoking is associated with increased arterial stiffness, which is partially reversible after just 4 weeks of smoking cessation.
Rehill et al. (2006) conducted an observational in Chronic tobacco smoking (n=120). Chronic tobacco smoking vs. Nonsmokers was evaluated on Systemic augmentation index (AIx) (p=0.004). Chronic tobacco smoking was associated with a significantly higher systemic augmentation index compared to nonsmokers (median 17.25% vs 11.75%, P=0.004).
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