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March 20, 2007HypertensionOpen Access

Impact of Smoking and Smoking Cessation on Arterial Stiffness and Aortic Wave Reflection in Hypertension

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Why the study?

Does smoking cessation improve arterial stiffness and aortic wave reflection in patients with essential hypertension?

Population

554 never-treated patients with essential hypertension aged 18 to 80 years, classified as current smokers…

Comparison

Current smoking and history of smoking vs Nonsmokers

Design

Cross-sectional

Authors

NJNoor A. JatoiPJPaula Jerrard-DunneJFJ. Feely

Discussion

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Overview

May support counseling on decade-long stiffness reversal in hypertensive smokers; leaves open causality and needs prospective confirmation.

Structured PICO

Does smoking cessation improve arterial stiffness and aortic wave reflection in patients with essential hypertension?

P
Population
554 never-treated patients with essential hypertension aged 18 to 80 years (56% females), classified as current smokers (n=150), ex-smokers (n=136), and nonsmokers (n=268).
I
Intervention
Current smoking and history of smoking (ex-smokers categorized into <1 year, >1 and <10 years, and >10 years of smoking cessation)
C
Comparator
Nonsmokers
O
Outcome
Aortic stiffness assessed as pulse wave velocity, wave reflection (augmentation index [AIx]), and transit time (T(R))surrogate

Smoking cessation is associated with a gradual improvement in arterial stiffness in hypertensive patients, with parameters normalizing after a decade of cessation.

Cite This Study

Jatoi et al. (2007) studied this question.

synapsesocial.com/papers/6a1a2e18f8467029b7b5060fhttps://doi.org/10.1161/hypertensionaha.107.087338
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