Why the study?
Do biophysical parameters such as phase angle and impedance components accurately estimate myocardial lesion size during in vitro RF catheter ablation?
Population
In vitro cardiac tissue
Comparison
Radio frequency catheter ablation with… vs Standard impedance monitoring alone
Design
Preclinical
Key result
Irreversible changes in reactive and resistive components of impedance, particularly phase angle, correlate better with in vitro RF ablation lesion size than impedance alone.
Authors
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May better estimate RF lesion size than impedance alone; hypothesis-generating for clinical use, needs in vivo validation.
Do biophysical parameters such as phase angle and impedance components accurately estimate myocardial lesion size during in vitro RF catheter ablation?
Monitoring phase angle and specific impedance components during RF ablation may provide a more accurate estimation of lesion size than standard impedance monitoring.
He et al. (2003) studied Radio frequency catheter ablation. Assessment of biophysical parameters (phase angle, capacitance, susceptance) vs. Impedance alone was evaluated on Correlation of biophysical parameters with lesion size. Irreversible changes in reactive and resistive components of impedance, particularly phase angle, correlate better with in vitro RF ablation lesion size than impedance alone.
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