Key result
A combination of electrical-based parameters measured 15 seconds after onset of RF energy in vitro explained 76% of the variability in lesion volume, outperforming single parameters.
Why the study?
Does a combination of early electrical-based parameters predict lesion volume during RF ablation in vitro better than single parameters?
Population
Cardiac tissue in vitro
Comparison
Measurement of a combination of electrical-based… vs Single parameters
Design
Preclinical
Follow-up
120 seconds
Authors
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Early electrical parameter combinations may predict RF lesion volume in vitro; hypothesis-generating for clinical ablation optimization.
Does a combination of early electrical-based parameters predict lesion volume during RF ablation in vitro better than single parameters?
Effect estimate: R2 0.76
Early changes in a combination of electrical parameters during RF ablation in vitro can accurately predict final lesion volume, potentially improving ablation efficacy in vivo.
Bosnos et al. (2010) studied Cardiac tissue in vitro. Radiofrequency (RF) energy ablation vs. Single parameter was evaluated on Lesion volume variability (R2) (R2 0.76). A combination of electrical-based parameters measured 15 seconds after onset of RF energy in vitro explained 76% of the variability in lesion volume, outperforming single parameters.
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